GlycemaCORE Whey Vanilla (14 servings) by Orthomolecular

GlycemaCORE Whey Protein is a drink mix formula that supports blood sugar balance already within normal levels. GlycemaCORE Whey Protein provides fiber, protein, omega-3 fatty acids, lipoic acid, chromium and vanadyl sulfate, with no added sugar. This formulation provides a whey protein base, responsibly sourced from grassfed cows in New Zealand, which serves as an alternative therapeutic option for patients. GlycemaCORE Whey Protein is available in delicious chocolate and vanilla flavors.

Overview

Maintaining normal blood sugar levels has become a concern for many in the United States and across the globe. The prevalence of refined sugars and carbohydrates and the low presence of fiber in the Western diet have been directly linked to many of the blood sugar challenges of this century. GlycemaCORE Whey Protein provides a helpful blend of nutrients that support the body’s response to sugar, signal optimal glucose disposal, increase cellular sensitivity to insulin, reduce glucose absorption and support microcirculation.

Glucomannan

Glucomannan is a water-soluble dietary fiber derived from konjac root (Amorphophallus konjac). A meta-analysis of 14 randomized controlled trials of glucomannan found 2.0-3.87

g/day significantly balanced total blood fats, reduced body weight by 0.79 kg and supported normal blood sugar levels. In one 28-day study, 3.6 g/day of glucomannan supplementation, given to 22 individuals, significantly promoted healthy blood fat and cholesterol profiles, Apo B and before-meal blood sugar levels, compared to placebo.

A review of seven clinical trials on glucomannan supplementation (2-4 g/day, for eight weeks) found the supplement significantly reduced body weight by 3.08-5.5 lbs, even without dietary restrictions. Even at low

doses of 1 g/day, over an eight-week period, consumption of glucomannan resulted in significant mean weight loss (5.5 lbs) in 20 subjects.

Guar Gum Fiber

Viscous dietary fibers are effective in maintaining satiety but challenging to apply in normal serving sizes in foods due to their viscosity and required high amounts. Guar gum fiber is a near non-viscous soluble fiber that has been proven effective in providing several physiological benefits. According to a 2016 summary of clinical research on the topic, regular intake of guar gum fiber provided significant sustained post-meal satiation effects and minimized the inter-meal calorie intake by about 20% in normal subjects. The intake of guar gum fiber alone or its combination with protein showed acute satiety effects in normal subjects.

Alpha Linolenic Acid

Flax seeds are a generous source of omega-3 fatty acids and fiber. The organic flax seeds in GlycemaCORE Whey Protein provide a total of 1.3 g of alpha linolenic acid per scoop, while contributing additional protein, lignans and numerous micronutrients.

Alpha Lipoic Acid

Alpha lipoic acid (ALA) is an antioxidant that has a potent effect on blood sugar metabolism. Recent studies have shown that ALA’s ability to regulate insulin is mediated by its activation of AMP-activated protein kinase (AMPK), which acts as a type of cellular fuel sensor to upregulate activity in the peripheral skeletal muscle. While in the hypothalamus, ALA downregulates AMPK, thereby reducing appetite. Administration of alpha lipoic acid in animal models was found to increase AMPK activity and fatty acid oxidation in skeletal muscle. ALA was also found to increase insulin-stimulated glucose disposal, both in whole body and in skeletal muscle.

One study, using oral dosing, showed that ALA increases insulin sensitivity by 27%. Other research has found that a dose of 600 mg/day of ALA over three months lead to a 36% reduction in blood fats and a 38%

improvement in the oxidative stress to oxidative defense ratio. ALA has also been shown to increase GLUT4 stimulated glucose transport, independent of insulin, to lower oxidative stress and to increase nerve conductivity in related neuropathy.

Chromium

Chromium is a critical element in the GTF, a complex shown to be crucial for glucose uptake into the cells. Studies using 1,000 mcg/day of chromium showed a significant improvement in

markers of blood sugar balance, insulin sensitivity and blood fats. In a study of 43 patients receiving either 600 mcg of chromium and 2 mg biotin a day or placebo, a significantly greater improvement for blood sugar was seen after four weeks, during the two-hour oral sugar test.

Vanadyl Sulfate

Vanadyl sulfate (VS) stimulates glucose uptake within cells helping to use blood sugar more efficiently and support blood sugar balance already within normal levels. VS increases GLUT-4 synthesis, a glucose transport protein which allows glucose to enter the cell. This improved glucose consumption promotes increased muscle cell sensitivity to insulin. 100 mg/day of VS was shown to support insulin sensitivity (fasting plasma glucose and HbA1c) in those with blood sugar imbalances.

In a three-week study, VS given at 100 mg/day significantly improved hepatic and peripheral muscle sensitivity in individuals with elevated blood sugar levels within the normal range. VS was also shown

to decrease endogenous glucose production by 20%.

Directions

Mix GlycemaCORE Whey Protein with 8-10 ounces of the beverage of your choice to the desired thickness, once daily or as recommended by your health care professional. Does Not Contain gluten, yeast, artificial colors and flavors.

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*This product is not intended to diagnose, treat or cure any illness or disease. The content and recommendations contained on this website have not been reviewed by the U.S. Food and Drug Administration (FDA) and are solely the opinion of the authors. Content contained on this website is not a substitute for professional medical advice, diagnosis or treatment. Never increase, reduce or discontinue any medication or treatment without first consulting your doctor.

***WARNING: (for California residents only) Consuming this product can expose you to chemicals including lead, which are known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65warnings.ca.gov/food***

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