Quercetin is an important flavonoid that provides free radical protection, promotes DNA integrity, and supports cellular regulation.* It has been studied for its support of healthy glutathione levels and inhibits glucose absorption in the intestines.* Alpha-Glycosyl Isoquercitrin delivers all the benefits of quercetin with better absorption and improved bioavailability.

N-Acetyl L-Cysteine (NAC) helps to replenish intracellular glutathione, which is vital in cellular antioxidant pathways.

Zinc Carnosine contains the PepZinGI brand of zinc-carnosine to support healthy gastrointestinal mucosa and relieve occasional mild gastric discomforts.* After years of development, a Japanese company produced PepZinGI®, a novel patented crystalline chelate compound consisting of L-carnosine and zinc. The zinc-carnosine complex is typically dosed one 75 mg capsule twice per day. This provides 16 mg of elemental zinc twice daily.

The ingredients in Cortisol Manager support healthy cortisol levels.* Cortisol is one of the most important hormones involved in the adaptation process. By supporting balanced cortisol and a healthy stress response, Cortisol Manager also promotes relaxation to support restful sleep.* THE ROLE OF CORTISOL IN TIMES OF STRESS Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol homeostasis is typically characterized by peak secretion during the early morning hours with a gradual decline throughout the day. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact. WITH HERBAL INGREDIENTS The ingredients in Cortisol Manager help support a balanced, adaptive cortisol response to stress.* Cortisol Manager contains a stress-reducing proprietary blend of Sensoril® brand ashwagandha (Withania somnifera) and Suntheanine™ brand L-theanine.* A proprietary blend of Magnolia (Magnolia officinalis) and epimedium (Epimedium koreanum), as well as phosphatidylserine from soy lecithin are included in Cortisol Manager. A 2008 placebo-controlled clinical trial showed that Sensoril® ashwagandha significantly reduced serum cortisol levels and helped manage stress compared to placebo, in subjects experiencing higher levels of stress.*¹ A 2018 placebo-controlled clinical trial showed that a single intake of Suntheanine™ L-theanine significantly increased alpha brain wave activity in subjects compared to their placebo counterparts.*² Alpha brain wave activity is associated with a more relaxed mental state.*² Together the ingredients in Cortisol Manager help support relaxation, to promote restful sleep.* They also help stabilize the stress hormone cortisol to further support a healthy stress response.*

The ingredients in Cortisol Manager Allergen Free support healthy cortisol levels.* Cortisol is one of the most important hormones involved in the adaptation process. By supporting balanced cortisol and a healthy stress response, Cortisol Manager Allergen Free also promotes relaxation to support restful sleep.* Cortisol Manager Allergen Free does not contain any of the top 8 most common food allergens and is ideal for patients with food sensitivities or food allergies. THE ROLE OF CORTISOL IN TIMES OF STRESS Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol homeostasis is typically characterized by peak secretion during the early morning hours with a gradual decline throughout the day. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact. WITH HERBAL INGREDIENTS The ingredients in Cortisol Manager Allergen Free help support a balanced, adaptive cortisol response to stress.* Cortisol Manager contains a stress-reducing proprietary blend of Sensoril® brand ashwagandha (Withania somnifera) and Suntheanine™ brand L-theanine.* A 2008 placebo-controlled clinical trial showed that Sensoril® ashwagandha significantly reduced serum cortisol levels and helped manage stress compared to placebo, in subjects experiencing higher levels of stress.*¹ A 2018 placebo-controlled clinical trial showed that a single intake of Suntheanine™ L-theanine significantly increased alpha brain wave activity in subjects compared to their placebo counterparts.*2 Alpha brain wave activity is associated with a more relaxed mental state.*² Together the ingredients in Cortisol Manager Allergen Free help support relaxation, to promote restful sleep.* They also help stabilize the stress hormone cortisol to further support a healthy stress response.* Cortisol Manager Allergen Free does not contain any of these common food allergens: milk, eggs, tree nuts, fish, shellfish, gluten, peanuts, soy, wheat, or yeast-derived ingredients.

WHAT IT DOES A MEDICAL FOOD FOR THE DIETARY MANAGEMENT OF MODERATE TO SEVERE IMPAIRED GI FUNCTION Physicians' Elemental Diet is a medical food designed for the dietary management of moderate to severe impaired gastrointestinal (GI) function, including irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and small intestinal bacterial overgrowth (SIBO). Physicians' Elemental Diet is designed to maintain nutritional sustenance as the sole source of nutrition for patients under medical supervision. HOW IT WORKS CLINICAL EVIDENCE OF ELEMENTAL DIETS Published clinical studies have shown that elemental diets are effective for the nutritional management of patients with moderate to severe impaired GI function.^1,2 In a clinical study of 93 patients with IBS and abnormal lactulose breath test scores, 80% of those who received an elemental diet had normalized test results with an associated improvement in clinical symptoms after 14 days.³ By 21 days, 85% of those patients saw improvement. Elemental diets can also be effective for managing IBD. In a controlled clinical study, 28 patients with active Crohn's disease received an elemental diet for 4 weeks with no other food or medication. Clinical remission was achieved in 71% of patients.⁴ REDUCES THE WORK OF DIGESTION, ALLOWING THE GUT TO REST AND RECUPERATE Physicians' Elemental Diet contains a balanced blend of macronutrients fortified with essential micronutrients and electrolytes to assure comprehensive support as the sole source of nutritional intake for limited periods. All the ingredients are in their simplest form for easy digestion and the product was designed with a well-tolerated flavor to encourage patient commitment to the diet. This hypoallergenic formula contains no intact proteins, polypeptides, corn, gluten, soy, or dairy.