WHAT IT DOES A MEDICAL FOOD FOR THE DIETARY MANAGEMENT OF MODERATE TO SEVERE IMPAIRED GI FUNCTION Physicians' Elemental Diet is a medical food designed for the dietary management of moderate to severe impaired gastrointestinal (GI) function, including irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and small intestinal bacterial overgrowth (SIBO). Physicians' Elemental Diet is designed to maintain nutritional sustenance as the sole source of nutrition for patients under medical supervision. HOW IT WORKS CLINICAL EVIDENCE OF ELEMENTAL DIETS Published clinical studies have shown that elemental diets are effective for the nutritional management of patients with moderate to severe impaired GI function.^1,2 In a clinical study of 93 patients with IBS and abnormal lactulose breath test scores, 80% of those who received an elemental diet had normalized test results with an associated improvement in clinical symptoms after 14 days.³ By 21 days, 85% of those patients saw improvement. Elemental diets can also be effective for managing IBD. In a controlled clinical study, 28 patients with active Crohn's disease received an elemental diet for 4 weeks with no other food or medication. Clinical remission was achieved in 71% of patients. REDUCES THE WORK OF DIGESTION, ALLOWING THE GUT TO REST AND RECUPERATE Physicians' Elemental Diet contains a balanced blend of macronutrients fortified with essential micronutrients and electrolytes to assure comprehensive support as the sole source of nutritional intake for limited periods. All the ingredients are in their simplest form for easy digestion and the product was designed with a well-tolerated flavor to encourage patient commitment to the diet. This hypoallergenic formula contains no intact proteins, polypeptides, corn, gluten, soy, or dairy.

The ingredients in Cortisol Manager support healthy cortisol levels.* Cortisol is one of the most important hormones involved in the adaptation process. By supporting balanced cortisol and a healthy stress response, Cortisol Manager also promotes relaxation to support restful sleep.* THE ROLE OF CORTISOL IN TIMES OF STRESS Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol homeostasis is typically characterized by peak secretion during the early morning hours with a gradual decline throughout the day. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact. WITH HERBAL INGREDIENTS The ingredients in Cortisol Manager help support a balanced, adaptive cortisol response to stress.* Cortisol Manager contains a stress-reducing proprietary blend of Sensoril® brand ashwagandha (Withania somnifera) and Suntheanine™ brand L-theanine.* A proprietary blend of Magnolia (Magnolia officinalis) and epimedium (Epimedium koreanum), as well as phosphatidylserine from soy lecithin are included in Cortisol Manager. A 2008 placebo-controlled clinical trial showed that Sensoril® ashwagandha significantly reduced serum cortisol levels and helped manage stress compared to placebo, in subjects experiencing higher levels of stress.*¹ A 2018 placebo-controlled clinical trial showed that a single intake of Suntheanine™ L-theanine significantly increased alpha brain wave activity in subjects compared to their placebo counterparts.*² Alpha brain wave activity is associated with a more relaxed mental state.*² Together the ingredients in Cortisol Manager help support relaxation, to promote restful sleep.* They also help stabilize the stress hormone cortisol to further support a healthy stress response.*

Quercetin is an important flavonoid that provides free radical protection, promotes DNA integrity, and supports cellular regulation.* It has been studied for its support of healthy glutathione levels and inhibits glucose absorption in the intestines.* Alpha-Glycosyl Isoquercitrin delivers all the benefits of quercetin with better absorption and improved bioavailability.

WHAT IT IS MULTI-NUTRIENT NUTRITIONAL SUPPLEMENT FOR MITOCHONDRIAL HEALTH* A unique combination of N-acetyl cysteine, acetyl L-carnitine, alpha-lipoic acid and other key nutrients that support mitochondrial functioning, based on the many years of clinical practice and ongoing research studies led by Dr. Jon Kaiser.* HOW IT WORKS SUPPORTS MITOCHONDRIAL FUNCTION* All cells, with the exception of red blood cells, contain mitochondria, organelles that produce adenosine triphosphate (ATP), the cellular "energy currency," from adenosine diphosphate (ADP). In addition, mitochondria are involved in many other processes within the body such as cell signaling and regulation of cellular metabolism. Mitochondrial energy metabolism is a critical part of cellular health and function. Mitochondrial function depends on quenching of free radicals produced during normal electron transport chain (ETC) activity, integrity of mitochondrial cell membranes and the transport of critical metabolites, such as fatty acids, into the mitochondria. One approach to supporting mitochondrial function is the provision of micronutrients and antioxidants that support these mechanisms.* K-PAX MitoNutrients is a unique combination of N-acetyl cysteine, acetyl L-carnitine, alpha-lipoic acid and other key nutrients that support mitochondrial functioning, based on the many years of clinical practice and ongoing research studies led by Dr. Kaiser.*

WHAT IT DOES PROVIDES ESSENTIAL OMEGA-3 FATTY ACIDS Pure Omega products provide a triglyceride form of omega-3 fatty acids sustainably sourced from anchovies, sardines, herring, tuna, and mackerel. Every lot of Pure Omega is tested for purity and labeled potency claims. The results of these tests are available to you using the lot number found on each bottle. Check your product purity here. HOW IT WORKS EPA & DHA HELP SUPPORT ESSENTIAL FUNCTIONS* Omega-3 essential polyunsaturated fatty acids have distinct chemical structures and physiologic functions that distinguish them from other families of essential fatty acids. Often lacking in Western diets, omega-3 fatty acids compete with other fatty acids in the body for cyclooxygenase (COX) and lipoxygenase (LOX) enzyme metabolism, incorporation into cell membranes, and the synthesis of lipid mediators.^1-3 The long-chain omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are almost exclusively marine-derived and act together to influence membrane fluidity and signal transduction pathways.⁴ EPA and DHA are abundantly enriched in the retina, brain, and heart tissues.^5-7 Each have preferential distribution within the phospholipid bilayer of cell membranes and have been shown to exert unique biological actions.⁴ Humans have limited capacity to endogenously produce EPA and DHA; therefore they are considered essential fatty acids. Dietary supplementation of EPA and DHA is an effective way to increase intake of these essential fatty acids.