Pyridoxal 5′ Phosphate 50 mg (100 caps) by Metabolic Maintenance

What is Pyridoxal 5’ Phosphate (P-5-P)? Pyridoxal 5’ Phosphate (P-5-P) is the phosphorylated form of vitamin B-6, which is the most bioavailable supplemental form of this critical nutrient.   How Does Pyridoxal 5’ Phosphate (P-5-P) Work?  P-5-P, arguably the most important member of the vitamin B-6 group, is the active coenzyme for more than 100 enzymes involved in the metabolism of proteins, lipids, and carbohydrates, thereby playing a key role in digestion and use of dietary nutrients throughout the body [1,2]. Furthermore, P-5-P facilitates the release of stored energy from your liver and muscles and facilitates the production of antibodies and red blood cells [3,4,5]. P-5-P also plays a critical role in both innate and adaptive immune responses [1]. In relation to the central nervous system, P-5-P-dependent enzymes are involved in the metabolism of the neurotransmitters dopamine, serotonin, glycine, epinephrine, norepinephrine, D-serine, L-glutamate, gamma-aminobutyric acid (GABA) and histamine, whose levels may be affected by P-5-P deficiency [6]. One important example is the formation of L-glutamate and its breakdown to GABA. L-glutamate and GABA are, respectively, the main excitatory and inhibitory neurotransmitters in the central nervous system [6]. P-5-P also helps to balance sodium and potassium levels by regulating the electrical functioning of nerves, heart and musculoskeletal system [4, 5]. Several severe neurological disorders and multifactorial neurological pathologies, such as autism, schizophrenia, Alzheimer’s disease, Parkinson’s disease, and some forms of epilepsy have been correlated to inadequate intracellular levels of P-5-P, further demonstrating a requirement of adequate P-5-P for the proper function of the nervous system [6]. Vitamin B-6 supplementation has also been shown to be beneficial for premenstrual comfort, nausea, and vomiting during pregnancy, and wrist nerve comfort [6].   What are the Suggested Uses For Pyridoxal 5’ Phosphate (P-5-P)?

• Essential metabolic nutrient for digestion and use of dietary fats, carbohydrates, and protein.*
• Essential nutrient for proper nerve function*
• Supports the normal formation of neurotransmitters*

  Source Materials: Ascorbic acid: corn sorbitol. Ascorbyl palmitate: ascorbic acid, palmitic aicd (palm oil). Pyridoxal 5’ phosphate: chemical synthesis. Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan and non-GMO.   Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, fish, shellfish, peanuts, tree nuts.   Recommendations: Use as directed by a healthcare professional.   Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.  

*This product is not intended to diagnose, treat or cure any illness or disease. The content and recommendations contained on this website have not been reviewed by the U.S. Food and Drug Administration (FDA) and are solely the opinion of the authors. Content contained on this website is not a substitute for professional medical advice, diagnosis or treatment. Never increase, reduce or discontinue any medication or treatment without first consulting your doctor.*