Magnesium’s benefits for enzyme activity, cardiac function, and energy metabolism are far reaching.^† As a required cofactor in more than 300 enzymes, magnesium plays a fundamental role in numerous cellular functions including energy production, skeletal and cardiac muscle excitability, neurochemical transmission, bone formation, insulin secretion, normal intracellular calcium, sodium and potassium levels, and the synthesis of carbohydrates, proteins, lipids, and nucleic acids.^† Albion^® amino acid chelate (magnesium bisglycinate chelate) is a highly absorbable and unusually well-tolerated form of magnesium. One of the prevalent pathways for magnesium absorption is via its formation of amino acid chelates which pass readily through the intestinal epithelium. Its low molecular weight and size allows it to be readily absorbed without dissociation and binding to a carrier. Unlike many forms of magnesium that commonly cause digestive disturbances including diarrhea, Albion^® magnesium bisglycinate chelate rarely causes side effects. Albion’s unique manufacturing process produces a true chelate in which the mineral and amino acid form a unique three-dimensional structure which protects the mineral compound from unwanted interactions during digestion yielding a highly bioavailable, natural absorptive form of magnesium.

Lithium orotate is a trace mineral that may help boost and balance mood.^† Lithium orotate is thought by some to have superior absorption compared to other lithium salts.¹ Each capsule provides 4.8 mg of elemental lithium.

A comprehensive, high-potency, hypoallergenic vitamin supplement in three capsules daily, LDA Multi-Vitamin has been formulated with higher strength amounts and specific ratios of essential vitamins compared to other Klaire Labs® multivitamin formulas. LDA Multi-Vitamin should be taken with food.

Used for formation of T3 and T4 thyroid hormones, L-tyrosine is also an important precursor for brain-stimulating catecholamines (dopamine, norepinephrine, and epinephrine) which support stress response mechanisms and the ability to concentrate.^† Supplies 500 mg of L-tyrosine USP per vegetarian capsule.

Folate deficiencies are common as many individuals do not consume enough folate-rich foods and folate is readily destroyed by cooking or processing. Although typically included in multivitamins, some individuals do not effectively methylate and convert folic acid into its bioactive form thus are still at risk of deficiency. L-5-MTHF, an active, methylated form of folate, requires no additional metabolic steps to be used by the body, thus it is often the preferred choice for women, children, and those with absorption or metabolic defects. L-5-MTHF efficiently supports methylation, DNA biosynthesis, homocysteine metabolism, and nervous system function.^† Supplies 1,700 mcg DFE folate per capsule.

L-Carnosine is a dipeptide compound that supports healthy cell function by two important mechanisms: it protects cells against free radicals and inhibits protein glycation, a major cause of aging of brain, skin, and other body tissues.^†

Increased demands for L-arginine, a conditionally essential amino acid, can occur during periods of increased physical stress or illness. L-arginine supports growth hormone metabolism, tissue integrity, energy metabolism, and immune function.^† It also supports the synthesis of nitric oxide, a molecule produced in all body tissues that serves an important role in the cardiovascular, immune, endocrine, and nervous systems in the body.^†

BioCell Collagen^® is a concentrated source of bioavailable, hydrolyzed collagen type II, chondroitin sulfate, and hyaluronic acid. A patented process produces a low molecular weight mixture of components that are easily absorbed and readily available for use in the body to protect connective tissues, promote cartilage synthesis, support repair, and improve the overall appearance of the skin.^† Collagen type II, the most abundant protein found in joint cartilage, helps support new cartilage synthesis and quenches free radicals in joint tissue.^† Hyaluronic acid is an important nourishing agent that helps to retain the natural moisture content of skin tissue and joint fluids.^† Chondroitin sulfate supports synthesis of cartilage tissue and inhibits cartilage-degrading enzymes.^† OptiMSM^®, a sulfur and methyl donor, supports joint structure and comfort. Vitamin C is required for hydroxylation, a biochemical process required for cartilage synthesis.^† Two capsules twice daily supplies approximately 1 g of collagen type II protein, 400 mg of chondroitin sulfate, 200 mg of hyaluronic acid, and 1 g of OptiMSM^®.

Iodine is an essential element. Although its main function is in the production of thyroid hormones T3 and T4, other organs in the body have a need for iodine in order to function normally.

Biofilm consists of microorganisms encased within a self-produced matrix of exopolysaccharides and exoproteins that strongly adheres to interfaces and resists dislodgement. Microorganisms residing within biofilms are highly resistant to antimicrobials including antibiotics and bacteriocins produced by probiotics. InterFase^® is a unique enzyme formulation that is especially designed to disrupt the biofilm matrix that embeds gastrointestinal organisms.^† Enzymes in InterFase^® are selected for their ability to lyse the extracellular polymers commonly found in biofilm as well as degrade bacterial and yeast cell wall structures.^† The enzyme blend in InterFase^® was developed using in vitro testing of antibiofilm activity and was found to have significant antibiofilm activity resulting in meaningful degradation of undesirable biofilm communities.^† InterFase^® is intended for use in conjunction with efforts to support normal gastrointestinal function and microbiota.^† As an adjunct, it is best combined with use of a high-strength, broad-spectrum, multispecies probiotic formulation and a prebiotic to encourage the formation of healthy intestinal microbial biofilm communities.^† The capsules should be taken away from meals to maximize the enzyme effects.